Type: Package Package: RobinCar2 Title: ROBust INference for Covariate Adjustment in Randomized Clinical Trials Version: 0.2.4.9000 Date: 2026-10-12 Authors@R: c( person("Liming", "Li", , "liming.li1@astrazeneca.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0008-6870-0878")), person("Marlena", "Bannick", , "mnorwood@uw.edu", role="aut", comment=c(ORCID="0000-0001-6279-5978")), person("Daniel", "Sabanes Bove", , "daniel@rconis.com", role = "aut", comment = c(ORCID = "0000-0002-0176-9239")), person("Dong", "Xi", , "Dong.Xi1@gilead.com", role = "aut"), person("Ting", "Ye", , "tingye1@uw.edu", role="aut"), person("Yanyao", "Yi", , "yi_yanyao@lilly.com", role="aut"), person("Gregory", "Chen", , "xiangyi.gregory.chen@msd.com", role = "ctb"), person("Gilead Sciences, Inc.", role = c("cph", "fnd")), person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")), person("Merck Sharp & Dohme, Inc.", role = c("cph", "fnd")), person("AstraZeneca plc", role = c("cph", "fnd")), person("Eli Lilly and Company", role = c("cph", "fnd")), person("Novartis Pharma AG", role = c("cph", "fnd")), person("The University of Washington", role = c("cph", "fnd")) ) Description: Performs robust estimation and inference when using covariate adjustment and/or covariate-adaptive randomization in randomized controlled trials. This package is trimmed to reduce the dependencies and validated to be used across industry. See "FDA's final guidance on covariate adjustment", Tsiatis (2008) , Bugni et al. (2018) , Ye, Shao, Yi, and Zhao (2023), Ye, Shao, and Yi (2022), Rosenblum and van der Laan (2010), Wang et al. (2021), Ye, Bannick, Yi, and Shao (2023), and Bannick, Shao, Liu, Du, Yi, and Ye (2024). License: Apache License 2.0 URL: https://github.com/openpharma/RobinCar2/ BugReports: https://github.com/openpharma/RobinCar2/issues Depends: R (>= 3.6) Imports: checkmate, numDeriv, MASS, sandwich, stats, survival, utils Suggests: knitr, rmarkdown, speff2trial, testthat (>= 3.0) VignetteBuilder: knitr Config/testthat/edition: 3 Encoding: UTF-8 Language: en-US LazyData: true Roxygen: list(markdown = TRUE) Config/roxygen2/version: 8.1.0 Repository: https://openpharma.r-universe.dev Date/Publication: 2026-10-19 12:53:36 UTC RemoteUrl: https://github.com/openpharma/RobinCar2 RemoteRef: HEAD RemoteSha: da87b40f1bbbb54b360a52cf586187323668c626 NeedsCompilation: no Packaged: 2026-10-19 13:54:38 UTC; root Author: Liming Li [aut, cre] (ORCID: ), Marlena Bannick [aut] (ORCID: ), Daniel Sabanes Bove [aut] (ORCID: ), Dong Xi [aut], Ting Ye [aut], Yanyao Yi [aut], Gregory Chen [ctb], Gilead Sciences, Inc. [cph, fnd], F. Hoffmann-La Roche AG [cph, fnd], Merck Sharp & Dohme, Inc. [cph, fnd], AstraZeneca plc [cph, fnd], Eli Lilly and Company [cph, fnd], Novartis Pharma AG [cph, fnd], The University of Washington [cph, fnd] Maintainer: Liming Li