{ "_id": "6a5dccd79baadeef8ab54b91", "Type": "Package", "Package": "savvyr", "Title": "Survival Analysis for AdVerse Events with VarYing Follow-Up\nTimes", "Version": "0.1.2", "Date": "2025-04-15", "Authors@R": "c(\nperson(\"Thomas\", \"Kuenzel\", email = \"thomas.kuenzel@roche.com\", role = c(\"aut\", \"cre\")),\nperson(\"Kaspar\", \"Rufibach\", email = \"kaspar.rufibach@roche.com\", role = \"aut\"),\nperson(\"Regina\", \"Stegherr\", email = \"regina.stegherr@uni-ulm.de\", role = \"aut\"),\nperson(\"Daniel\", \"Sabanés Bové\", email = \"daniel@rconis.com\", role = \"aut\"),\nperson(\"F. Hoffmann-La Roche AG\", role = c(\"cph\", \"fnd\")),\nperson(\"Universität Ulm\", role = c(\"cph\", \"fnd\"))\n)", "Description": "The SAVVY (Survival Analysis for AdVerse Events with\nVarYing Follow-Up Times) project is a consortium of academic\nand pharmaceutical industry partners that aims to improve the\nanalyses of adverse event (AE) data in clinical trials through\nthe use of survival techniques appropriately dealing with\nvarying follow-up times and competing events, see Stegherr,\nSchmoor, Beyersmann, et al. (2021)\n. Although statistical\nmethodologies have advanced, in AE analyses often the incidence\nproportion, the incidence density or a non-parametric\nKaplan-Meier estimator are used, which either ignore censoring\nor competing events. This package contains functions to easily\nconduct the proposed improved AE analyses.", "License": "Apache License 2.0", "URL": "https://openpharma.github.io/savvyr/", "BugReports": "https://github.com/openpharma/savvyr/issues", "Config/Needs/documentation": "roxytypes, roxylint", "RdMacros": "Rdpack", "VignetteBuilder": "knitr", "Encoding": "UTF-8", "Language": "en-US", "RoxygenNote": "7.3.2", "Repository": "https://openpharma.r-universe.dev", "Date/Publication": "2025-05-07 15:18:04 UTC", "RemoteUrl": "https://github.com/openpharma/savvyr", "RemoteRef": "HEAD", "RemoteSha": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "NeedsCompilation": "no", "Packaged": { "Date": "2026-07-20 07:20:12 UTC", "User": "root" }, "Author": "Thomas Kuenzel [aut, cre],\nKaspar Rufibach [aut],\nRegina Stegherr [aut],\nDaniel Sabanés Bové [aut],\nF. Hoffmann-La Roche AG [cph, fnd],\nUniversität Ulm [cph, fnd]", "Maintainer": "Thomas Kuenzel ", "_user": "openpharma", "_type": "src", "_file": "savvyr_0.1.2.tar.gz", "_fileid": "https://r2.ropensci.org/42c7b6dc7b1293da2561a20aab7b7ab21af49a43cb527311211517243d6873c8", "_filesize": 741164, "_sha256": "42c7b6dc7b1293da2561a20aab7b7ab21af49a43cb527311211517243d6873c8", "_expires": "2026-10-28T07:23:01.000Z", "_created": "2026-07-20T07:20:12.000Z", "_published": "2026-07-20T07:23:03.127Z", "_jobs": [ { "job": 88293831059, "time": 133, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "8453635010" }, { "job": 88293831116, "time": 137, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "8453636228" }, { "job": 88293831074, "time": 100, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "8453623034" }, { "job": 88293831115, "time": 83, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "8453617522" }, { "job": 88293229650, "time": 214, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "8453587048" }, { "job": 88293831022, "time": 113, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "8453627814" }, { "job": 88293831054, "time": 70, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "8453613498" }, { "job": 88293831147, "time": 76, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "8453614635" }, { "job": 88293831066, "time": 70, "config": "windows-release", "r": "4.6.1", "check": "OK", "artifact": "8453612490" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060", "_status": "success", "_upstream": "https://github.com/openpharma/savvyr", "_commit": { "id": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "author": "Daniel Sabanes Bove ", "committer": "GitHub ", "message": "Update package version to 0.1.2, fix author email, and remove Bioconductor dependency (#31)\n\n", "time": 1746631084 }, "_maintainer": { "name": "Thomas Kuenzel", "email": "thomas.kuenzel@roche.com", "login": "kuenzelt", "description": "", "uuid": 122105979 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.0", "role": "Depends" }, { "package": "checkmate", "role": "Imports" }, { "package": "etm", "role": "Imports" }, { "package": "Rdpack", "role": "Imports" }, { "package": "kableExtra", "role": "Suggests" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "testthat", "version": ">= 3.0", "role": "Suggests" } ], "_owner": "openpharma", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 6, "_contributors": [ { "user": "danielinteractive", "count": 8, "uuid": 1071227 }, { "user": "kuenzelt", "count": 7, "uuid": 122105979 }, { "user": "cicdguy", "count": 2, "uuid": 26552821 }, { "user": "dgkf", "count": 1, "uuid": 18220321 }, { "user": "numbersman77", "count": 1, "uuid": 44927366 } ], "_userbio": { "uuid": 8436743, "type": "organization", "name": "openpharma", "followers": 263, "description": "Further precompetitive collaboration in life sciences" }, "_downloads": { "count": 341, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/savvyr" }, "_devurl": "https://github.com/openpharma/savvyr", "_pkgdown": "https://openpharma.github.io/savvyr/", "_searchresults": 1, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/NEWS.html", "extra/NEWS.txt", "extra/readme.html", "extra/readme.md", "extra/savvyr.html", "manual.pdf" ], "_homeurl": "https://github.com/openpharma/savvyr", "_realowner": "openpharma", "_cranurl": true, "_releases": [ { "version": "0.1.0", "date": "2024-02-20" }, { "version": "0.1.1", "date": "2024-06-10" }, { "version": "0.1.2", "date": "2025-05-08" } ], "_exports": [ "aalen_johansen", "generate_data", "inc_prop", "one_minus_kaplan_meier", "prop_trans_inc_dens", "prop_trans_inc_dens_ce" ], "_help": [ { "page": "aalen_johansen", "title": "Aalen Johansen Estimator", "topics": [ "aalen_johansen" ] }, { "page": "generate_data", "title": "Generate Example Data", "topics": [ "generate_data" ] }, { "page": "inc_prop", "title": "Computing the Incidence Proportion", "topics": [ "inc_prop" ] }, { "page": "one_minus_kaplan_meier", "title": "One Minus Kaplan-Meier", "topics": [ "one_minus_kaplan_meier" ] }, { "page": "prop_trans_inc_dens", "title": "Computing the Probability Transform Incidence Density", "topics": [ "prop_trans_inc_dens" ] }, { "page": "prop_trans_inc_dens_ce", "title": "Probability Transform Incidence Density Accounting for Competing Events", "topics": [ "prop_trans_inc_dens_ce" ] } ], "_pkglogo": "https://github.com/openpharma/savvyr/raw/HEAD/man/figures/logo.png", "_readme": "https://github.com/openpharma/savvyr/raw/HEAD/README.md", "_rundeps": [ "backports", "checkmate", "data.table", "etm", "lattice", "Matrix", "rbibutils", "Rcpp", "RcppArmadillo", "Rdpack", "survival" ], "_vignettes": [ { "source": "introduction.Rmd", "filename": "introduction.html", "title": "Introduction to savvyr", "engine": "knitr::rmarkdown", "headings": [ "Example using dummy data", "References" ], "created": "2024-02-16 13:01:15", "modified": "2024-02-16 13:01:15", "commits": 1 } ], "_score": 5.079181246047625, "_indexed": true, "_nocasepkg": "savvyr", "_universes": [ "openpharma", "kuenzelt" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.1.2", "date": "2026-07-20T07:22:27.000Z", "distro": "resolute", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/871e80ad65bf3059a1c91ce972782ed62191bca46857a4709c8f768a6cb1d428", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.6.1", "os": "linux", "version": "0.1.2", "date": "2026-07-20T07:22:28.000Z", "distro": "resolute", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/06978d40f35cc8fde53efc71558cacb5c669cbb4b374a1bd492cc1fa3ed9cf8e", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.5.3", "os": "mac", "version": "0.1.2", "date": "2026-07-20T07:21:53.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/1aa04bae1758fea3f7d3e55c9c54d58e40cff83ba23ca19a97a31c46c842c82d", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.6.1", "os": "mac", "version": "0.1.2", "date": "2026-07-20T07:21:39.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/f13081307e6efff6cc2bcdc40e056c41e3556d5ae07e9cb0bbf462a389b0b295", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.6.0", "os": "wasm", "version": "0.1.2", "date": "2026-07-20T07:22:21.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/3bd52e25cabf79f43a9d74ce89ed07f361b997dcfe85d15ee03e905c6be1eef6", "status": "success", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.7.0", "os": "win", "version": "0.1.2", "date": "2026-07-20T07:21:22.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/52f95d236719c15f4fadfdd0128c84f04302bf5d884c09514fbcdd292b9a347f", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.5.3", "os": "win", "version": "0.1.2", "date": "2026-07-20T07:21:26.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/0330f0f8d76a83a39c2d2775763111b32ad103ec95a167dc711577c3fb6717ef", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" }, { "r": "4.6.1", "os": "win", "version": "0.1.2", "date": "2026-07-20T07:21:18.000Z", "commit": "6b1eff7f8a9c60ed43ad759bcee42402bf685d6e", "fileid": "https://r2.ropensci.org/08bfd077f49a04e0040f37f1b1eda6d6591adee787cb5f65354f0f265e0ab384", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/openpharma/actions/runs/29724109060" } ] }