Package: simaerep
Title: Detect Clinical Trial Sites Over- or Under-Reporting Clinical
        Events
Version: 1.0.0
Authors@R: c(
    person(given = "Bjoern",
           family = "Koneswarakantha",
           role = c("aut", "cre", "cph"),
           email = "bjoern.koneswarakantha@roche.com",
           comment = c(ORCID = "0000-0003-4585-7799")),
    person("F. Hoffmann-La Roche Ltd",
           role = c("cph"))
  )
Description: Monitoring reporting rates of subject-level clinical
        events (e.g. adverse events, protocol deviations) reported by
        clinical trial sites is an important aspect of risk-based
        quality monitoring strategy. Sites that are under-reporting or
        over-reporting events can be detected using bootstrap
        simulations during which patients are redistributed between
        sites. Site-specific distributions of event reporting rates are
        generated that are used to assign probabilities to the observed
        reporting rates. (Koneswarakantha 2024
        <doi:10.1007/s43441-024-00631-8>).
URL: https://openpharma.github.io/simaerep/,
        https://github.com/openpharma/simaerep/
License: MIT + file LICENSE
Encoding: UTF-8
Depends: R (>= 4.0), ggplot2
Imports: dplyr (>= 1.1.0), tidyr (>= 1.1.0), magrittr, purrr, rlang,
        stringr, forcats, cowplot, RColorBrewer, furrr (>= 0.2.1),
        progressr, knitr, tibble, dbplyr, glue
Suggests: testthat, devtools, pkgdown, spelling, haven, vdiffr, lintr,
        DBI, duckdb, ggExtra
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Language: en-US
Config/testthat/edition: 3
Config/pak/sysreqs: libicu-dev
Repository: https://openpharma.r-universe.dev
Date/Publication: 2025-10-28 11:20:32 UTC
RemoteUrl: https://github.com/openpharma/simaerep
RemoteRef: HEAD
RemoteSha: 06b10e9388ef1185480be0a75783d79f1d9a1fac
NeedsCompilation: no
Packaged: 2026-05-26 06:56:29 UTC; root
Author: Bjoern Koneswarakantha [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0003-4585-7799>),
  F. Hoffmann-La Roche Ltd [cph]
Maintainer: Bjoern Koneswarakantha <bjoern.koneswarakantha@roche.com>