Package: tipse
Title: Tipping Point Analysis for Survival Endpoints
Version: 2.1
Authors@R: 
      c(person(given = "Ajmal", 
           family = "Oodally", 
           email = "ajmaloodally@hotmail.com", 
           role = c("cre", "aut"),
           comment = c(ORCID = "0000-0001-8143-5011")
           ),
    person(given = "Craig", 
           family = "Wang", 
           email = "craig.wang@novartis.com", 
           role = c("aut"), 
           comment = c(ORCID = "0000-0003-1804-2463")
           ),
    person(given = "Zheng", 
           family = "Li", 
           email = "zheng.li@novartis.com", 
           role = c("ctb"),
           comment = c(ORCID = "0000-0002-7655-0290")
           ))
Description: Implements tipping point sensitivity analysis for
        time-to-event endpoints under different missing data scenarios,
        as described in Oodally et al. (2025)
        <doi:10.48550/arXiv.2506.19988>. Supports both model-based and
        model-free imputation, multiple imputation workflows,
        plausibility assessment and visualizations. Enables robust
        assessment for regulatory and exploratory analyses.
License: GPL (>= 3)
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
URL: https://github.com/openpharma/tipse
Depends: R (>= 3.5)
LazyData: true
Imports: MASS, ggplot2, survival, dplyr, stats, utils, knitr, purrr,
        rmarkdown
VignetteBuilder: knitr
Suggests: testthat (>= 3.0.0)
Config/testthat/edition: 3
Config/roxygen2/version: 8.1.0
Config/pak/sysreqs: cmake make libuv1-dev
Repository: https://openpharma.r-universe.dev
Date/Publication: 2026-08-21 08:15:11 UTC
RemoteUrl: https://github.com/openpharma/tipse
RemoteRef: HEAD
RemoteSha: 2fd8f197e0310d11de9bee14a233d588c1a3a790
NeedsCompilation: no
Packaged: 2026-09-21 09:33:01 UTC; root
Author: Ajmal Oodally [cre, aut] (ORCID:
    <https://orcid.org/0000-0001-8143-5011>),
  Craig Wang [aut] (ORCID: <https://orcid.org/0000-0003-1804-2463>),
  Zheng Li [ctb] (ORCID: <https://orcid.org/0000-0002-7655-0290>)
Maintainer: Ajmal Oodally <ajmaloodally@hotmail.com>